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Publications

Phenotypic models of evolution and development: Geometry as destiny

Cornell Affiliated Author(s)
Author
P. François
E.D. Siggia
Abstract

Quantitative models of development that consider all relevant genes typically are difficult to fit to embryonic data alone and have many redundant parameters. Computational evolution supplies models of phenotype with relatively few variables and parameters that allows the patterning dynamics to be reduced to a geometrical picture for how the state of a cell moves. The clock and wavefront model, that defines the phenotype of somitogenesis, can be represented as a sequence of two discrete dynamical transitions (bifurcations).

Journal
Current Opinion in Genetics and Development
Date Published
Funding Source
PHY-0954398
R01GM101653
RGPIN 401950-11
Research Area

Fluctuation broadening in carbon nanotube resonators

Cornell Affiliated Author(s)
Author
A.W. Barnard
V. Sazonova
A.M. Van Der Zande
P.L. McEuen
Abstract

We simulated the behavior of suspended carbon nanotube resonators over a broad range of temperatures to explore the physics of semiflexible polymers in underdamped environments. We find that thermal fluctuations induce strong coupling between resonance modes. This effect leads to spectral fluctuations that readily account for the experimentally observed quality factors Q ∼ 100 at 300 K. Using a mean-field approach to describe fluctuations, we analytically calculate Q and frequency shifts in tensioned and buckled carbon nanotubes and find excellent agreement with simulations.

Journal
Proceedings of the National Academy of Sciences of the United States of America
Date Published
Funding Source
0520404
0654193
0928552
Group (Lab)
Paul McEuen Group

Edge states for topological insulators in two dimensions and their Luttinger-like liquids

Cornell Affiliated Author(s)
Author
D. Bernard
Eun-Ah Kim
A. Leclair
Abstract

Topological insulators in three spatial dimensions are known to possess a precise bulk-boundary correspondence, in that there is a one-to-one correspondence between the five classes characterized by bulk topological invariants and Dirac Hamiltonians on the boundary with symmetry protected zero modes. This holographic characterization of topological insulators is studied in two dimensions. Dirac Hamiltonians on the one-dimensional edge are classified according to the discrete symmetries of time reversal, particle hole, and chirality, extending a previous classification in two dimensions.

Journal
Physical Review B - Condensed Matter and Materials Physics
Date Published
Group (Lab)

Strong enhancement of light-matter interaction in graphene coupled to a photonic crystal nanocavity

Cornell Affiliated Author(s)
Author
X. Gan
K.F. Mak
Y. Gao
Y. You
F. Hatami
J. Hone
T.F. Heinz
D. Englund
Abstract

We demonstrate a large enhancement in the interaction of light with graphene through coupling with localized modes in a photonic crystal nanocavity. Spectroscopic studies show that a single atomic layer of graphene reduces the cavity reflection by more than a factor of one hundred, while also sharply reducing the cavity quality factor. The strong interaction allows for cavity-enhanced Raman spectroscopy on subwavelength regions of a graphene sample. A coupled-mode theory model matches experimental observations and indicates significantly increased light absorption in the graphene layer.

Journal
Nano Letters
Date Published
Group (Lab)
Kin Fai Mak Group

Structural and kinetic effects on changes in the CO2 binding pocket of human carbonic anhydrase II

Cornell Affiliated Author(s)
Author
D. West
C.U. Kim
C. Tu
A.H. Robbins
Sol Gruner
D.N. Silverman
R. McKenna
Abstract

This work examines the effect of perturbing the position of bound CO 2 in the active site of human carbonic anhydrase II (HCA II) on catalysis. Variants of HCA II in which Val143 was replaced with hydrophobic residues Ile, Leu, and Ala were examined. The efficiency of catalysis in the hydration of CO2 for these variants was characterized by 18O exchange mass spectrometry, and their structures were determined by X-ray crystallography at 1.7-1.5 Å resolution.

Journal
Biochemistry
Date Published
Research Area
Group (Lab)
Sol M. Gruner Group

A tunable low-energy photon source for high-resolution angle-resolved photoemission spectroscopy

Cornell Affiliated Author(s)
Author
J.W. Harter
P.D.C. King
E.J. Monkman
D.E. Shai
Y. Nie
M. Uchida
B. Burganov
S. Chatterjee
K.M. Shen
Abstract

We describe a tunable low-energy photon source consisting of a laser-driven xenon plasma lamp coupled to a Czerny-Turner monochromator. The combined tunability, brightness, and narrow spectral bandwidth make this light source useful in laboratory-based high-resolution photoemission spectroscopy experiments. The source supplies photons with energies up to ∼7 eV, delivering under typical conditions >1012 ph/s within a 10 meV spectral bandwidth, which is comparable to helium plasma lamps and many synchrotron beamlines.

Journal
Review of Scientific Instruments
Date Published
Funding Source
DMR-0847385
DMR-1120296
Group (Lab)
Kyle Shen Group

Effect of cation sublattice ordering on structure and raman scattering of znGeN2

Cornell Affiliated Author(s)
Author
E. Blanton
K. He
J. Shan
K. Kash
Abstract

The semiconductor ZnGeN2 was grown by a vapor-liquid-solid mechanism. Ordering of the Zn-Ge sublattice with growth temperature and Zn partial pressure was investigated by powder X-ray diffraction and was found to be sensitive to the growth temperature and insensitive, over the range explored, to the Zn and NH3 partial pressures. The degree of disorder on the cation sublattice was observed to correlate with the suppression of predicted Raman peaks and the emergence of phonon density-of-states features. © 2013 Materials Research Society.

Conference Name
structure
Date Published
Funding Source
1006132
Group (Lab)
Jie Shan Group

Electronic liquid crystal physics of underdoped cuprates

Cornell Affiliated Author(s)
Author
Eun-Ah Kim
M.J. Lawler
Abstract

Recent observations of broken symmetries have partly demystified the pseudogap phase. Here we review evidence for long-range intra-unit-cell (IUC) nematic order and its unexpectedly strong coupling to the phase of the fluctuating stripes in the pseudogap states of underdoped Bi 2Sr 2CaCu 2O 8+δ.

Journal
Physica C: Superconductivity and its Applications
Date Published
Funding Source
DMR-0955822
DMR-1120296
0520404
Group (Lab)
Michael Lawler Group

Generalized rotational susceptibility studies of solid 4He

Cornell Affiliated Author(s)
Author
V. Gadagkar
E.J. Pratt
B. Hunt
M. Yamashita
M.J. Graf
A.V. Balatsky
J.C. Davis
Abstract

Using a novel SQUID-based torsional oscillator (TO) technique to achieve increased sensitivity and dynamic range, we studied TO's containing solid 4He. Below ∼250 mK, the TO resonance frequency f increases and its dissipation D passes through a maximum as first reported by Kim and Chan. To achieve unbiased analysis of such 4He rotational dynamics, we implemented a new approach based upon the generalized rotational susceptibility χ 4He -1(ω, T ).

Journal
Journal of Low Temperature Physics
Date Published
Group (Lab)
J.C. Seamus Davis Group