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Cornell University

Eric Siggia Group

Publications

Publications from 1970 - 2009

Additional Publications

2014

Encoding of temporal signals by the TGF-β Pathway and implications for embryonic patterning

Sorre B, Warmflash A, Brivanlou AH, Siggia E. Encoding of temporal signals by the TGF-β Pathway and implications for embryonic patterning. Developmental Cell. 2014;30(3):334-342, .

2013

Decisions on the fly in cellular sensory systems

Siggia ED, Vergassola M. Decisions on the fly in cellular sensory systems. Proceedings of the National Academy of Sciences of the United States of America. 2013;110(39):E3704-E3712, .

Phenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonism

François P, Voisinne G, Siggia ED, Altan-Bonnet G, Vergassola M. Phenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonism. Proceedings of the National Academy of Sciences of the United States of America. 2013;110(10):E888-E897, .

2012

Phenotypic models of evolution and development: Geometry as destiny

François P, Siggia ED. Phenotypic models of evolution and development: Geometry as destiny. Current Opinion in Genetics and Development. 2012;22(6):627-633, .

Pareto evolution of gene networks: An algorithm to optimize multiple fitness objectives

Warmflash A, François P, Siggia ED. Pareto evolution of gene networks: An algorithm to optimize multiple fitness objectives. Physical Biology. 2012;9(5).

Signaling dynamics and embryonic development

Warmflash A, Siggia ED, Brivanlou AH. Signaling dynamics and embryonic development. Cell Cycle. 2012;11(19):3529-3530, .

Adaptive temperature compensation in circadian oscillations

François P, Despierre N, Siggia ED. Adaptive temperature compensation in circadian oscillations. PLoS Computational Biology. 2012;8(7).

Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4

Warmflash A, Zhang Q, Sorre B, Vonic A, Siggia ED, Brivanlou AH. Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4. Proceedings of the National Academy of Sciences of the United States of America. 2012;109(28):E1947-E1956, .

Geometry, epistasis, and developmental patterning

Corson F, Siggia ED. Geometry, epistasis, and developmental patterning. Proceedings of the National Academy of Sciences of the United States of America. 2012;109(15):5568-5575, .

2010

Predicting embryonic patterning using mutual entropy fitness and in silico evolution

François P, Siggia ED. Predicting embryonic patterning using mutual entropy fitness and in silico evolution. Development. 2010;137(14):2385-2395, .