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Cornell University

Eric Siggia Group

Publications

Publications from 1970 - 2009

Additional Publications

2019

A 3D model of a human epiblast reveals BMP4-driven symmetry breaking

Simunovic M, Metzger JJ, Etoc F, Yoney A, Ruzo A, Martyn I, et al. A 3D model of a human epiblast reveals BMP4-driven symmetry breaking. Nature Cell Biology. 2019;21(7):900-910, .

Self-organization of stem cells into embryos: A window on early mammalian development

Shahbazi MN, Siggia ED, Zernicka-Goetz M. Self-organization of stem cells into embryos: A window on early mammalian development. Science. 2019;364(6444):948-951, .

A wave of WNT signaling balanced by secreted inhibitors controls primitive streak formation in micropattern colonies of human embryonic stem cells

Martyn I, Brivanlou AH, Siggia ED. A wave of WNT signaling balanced by secreted inhibitors controls primitive streak formation in micropattern colonies of human embryonic stem cells. Development (Cambridge). 2019;146(6).

Mapping cell migrations and fates in a gastruloid model to the human primitive streak

Martyn I, Siggia ED, Brivanlou AH. Mapping cell migrations and fates in a gastruloid model to the human primitive streak. Development (Cambridge). 2019;146(17).

2018

Erratum to: Self-organization of a human organizer by combined Wnt and Nodal signalling (Nature, (2018), 558, 7708, (132-135), 10.1038/s41586-018-0150-y)

Martyn I, Kanno TY, Ruzo A, Siggia ED, Brivanlou AH. Erratum to: Self-organization of a human organizer by combined Wnt and Nodal signalling (Nature, (2018), 558, 7708, (132-135), 10.1038/s41586-018-0150-y). Nature. 2018;564(7735):E10+.

WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids

Yoney A, Etoc F, Ruzo A, Carroll T, Metzger JJ, Martyn I, et al. WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids. eLife. 2018;7.

Self-organization of a human organizer by combined Wnt and Nodal signaling

Martyn I, Kanno TY, Ruzo A, Siggia ED, Brivanlou AH. Self-organization of a human organizer by combined Wnt and Nodal signaling. Nature. 2018;558(7708):132-135, .

Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning

Morgani SM, Metzger JJ, Nichols J, Siggia ED, Hadjantonakis AK. Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning. eLife. 2018;7.

Modeling Mammalian Gastrulation With Embryonic Stem Cells

Siggia ED, Warmflash A. Modeling Mammalian Gastrulation With Embryonic Stem Cells. Human Embryonic Stem Cells in Development. 2018;129:1-23, .

2017

Gene-free methodology for cell fate dynamics during development

Corson F, Siggia ED. Gene-free methodology for cell fate dynamics during development. eLife. 2017;6.