Protein dynamical transition at 110 K
Abstract
Proteins are known to undergo a dynamical transition at around 200 K but the underlying mechanism, physical origin, and relationship to water are controversial. Here we report an observation of a protein dynamical transition as low as 110 K. This unexpected protein dynamical transition precisely correlated with the cryogenic phase transition of water from a high-density amorphous to a low-density amorphous state. The results suggest that the cryogenic protein dynamical transition might be directly related to the two liquid forms of water proposed at cryogenic temperatures.
Date Published
Journal
Proceedings of the National Academy of Sciences of the United States of America
Volume
108
Issue
52
Number of Pages
20897-20901,
URL
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862932863&doi=10.1073%2fpnas.1110840108&partnerID=40&md5=3fa1b3362fdb9260417e028cd6ba18a9
DOI
10.1073/pnas.1110840108
Research Area
Group (Lab)
Sol M. Gruner Group